What is NEXLIZET?
NEXLIZET is a nonstatin, once-daily pill for adults with known heart disease or an inherited condition that causes high levels of bad cholesterol, who need additional lowering of bad cholesterol.
Who should not take NEXLIZET?
Do not take NEXLIZET if you are allergic to ezetimibe tablets. Ezetimibe, one of the ingredients in NEXLIZET, can cause serious allergic reactions. Stop taking NEXLIZET and call your doctor, or go to the nearest emergency room, if you have the following:
- swelling of your face, lips, mouth, or tongue
- wheezing or trouble breathing
- severe itching and/or skin rashes, redness, or swelling
- dizziness or fainting
- fast heartbeat or pounding in your chest
How should I take NEXLIZET?
Take NEXLIZET exactly as your doctor tells you to take it. NEXLIZET should be taken once daily, with or without food. Do not take more than 1 dose per day. If you miss a dose, talk to your doctor.
Swallow the NEXLIZET tablet whole. Do not cut, chew, or crush the tablet.
If you take a medicine that lowers cholesterol by binding bile acids, such as colesevelam or cholestyramine, take NEXLIZET at least 2 hours before, or 4 hours after, you take bile acid binding medicines. Ask your doctor if you are not sure if you take these medicines.
Do I still have to eat healthy and exercise while taking NEXLIZET?
Yes, NEXLIZET should be combined with diet, exercise, and a statin.
Can I take NEXLIZET if I’m already taking a statin?
Yes, NEXLIZET should be taken with statins.
Is NEXLIZET safe to take?
NEXLIZET can cause side effects that can become serious, including:
- high levels of uric acid in the blood, which can lead to gout, a painful joint condition. Call your doctor if you have any of the following symptoms:
- severe foot pain, especially in the toe joint
- warm joints
- tender joints
- joint redness
- tendon problems: Stop taking NEXLIZET immediately and get medical help right away if you get any of the following signs or symptoms of tendon rupture:
- hear or feel a snap or pop in a tendon area
- bruising right after an injury in a tendon area
- unable to move the affected area or put weight on the affected area
Tell your doctor right away about any side effect you experience. NEXLIZET can cause side effects, including:
- symptoms of the common cold or flu
- muscle spasms
- back pain
- stomach pain
- pain in the shoulders, legs, or arms
Your doctor may check your blood for side effects that you might not be able to feel.
These are not all the possible side effects of NEXLIZET. For more information, ask your doctor or pharmacist.
What should I tell my doctor before taking NEXLIZET?
Tell your doctor if you:
- have ever had an allergic reaction to ezetimibe
- have, or have ever had, gout
- have, or have ever had, tendon problems
- are pregnant or breastfeeding, or may become pregnant or plan to breastfeed
- have severe kidney problems
- have moderate or severe liver problems
- are taking simvastatin, pravastatin, cyclosporine, fibrates, or cholestyramine