What is NEXLETOL?
NEXLETOL is a prescription medicine used:
-
to lower the risk of heart attack and heart procedures like stent placement or bypass surgery, in adults who are unable to take recommended statin treatment (a cholesterol-lowering medicine), or are not taking a statin, who:
- have known heart disease, or
- are at high risk for heart disease but without known heart disease
- along with diet and other cholesterol-lowering medicines, or alone when use with other cholesterol-lowering medicines is not possible, to reduce low-density lipoprotein (LDL or bad cholesterol) in adults with high blood cholesterol levels called primary hyperlipidemia, including a type of high blood cholesterol called heterozygous familial hypercholesterolemia (HeFH)
How should I take NEXLETOL?
Take NEXLETOL exactly as your doctor tells you to take it. NEXLETOL should be taken once daily, with or without food.
Can I take NEXLETOL if I’m already taking a statin?
Take NEXLETOL exactly as your doctor prescribes. He or she may prescribe statins or other
Is NEXLETOL safe to take?
The safety of bempedoic acid, a component of NEXLETOL, was studied in 4 clinical trials of more than
The most common side effects of NEXLETOL in people with primary hyperlipidemia include:
- symptoms of the common cold or flu-like symptoms
- back pain
- stomach pain
- increased liver enzymes
- muscle spasms
- pain in shoulder, legs, or arms
- anemia
- bronchitis
The most common side effects of NEXLETOL in people with heart problems include:
- kidney problems
- anemia
- increased liver enzymes
- muscle spasms
- gallstones
These are not all the possible side effects of NEXLETOL. For more information, ask your healthcare provider or pharmacist.
What should I tell my doctor before taking NEXLETOL?
Tell your healthcare provider if you:
- have, or had, gout
- have, or had, tendon problems
- are pregnant or breastfeeding or may become pregnant or plan to breastfeed. It is not known if NEXLETOL passes into your breastmilk
- have severe kidney or severe liver problems
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
Especially tell your healthcare provider if you take or plan to take simvastatin or pravastatin, as taking either with NEXLETOL may increase your risk of developing muscle pain or weakness.